Abstract
Both cancer and diabetes are significant health-care challenges, and the coexistence of these diseases has been linked with increased mortality. To safely and effectively manage the patient with cancer and diabetes, the advanced practitioner needs a working knowledge of the underlying pathobiology of both diseases, common underlying risk factors, the heterogeneity of each cancer diagnosis, and improvements in treatment approaches for both diseases. Collaboration between advanced practice professionals in oncology, primary care, endocrinology, and nutrition can provide the initial support and continued management needed by the patient with cancer, diabetes, and other comorbidities, as illustrated by the case report included in this review. Familiarity with the diagnostic evaluation of patients at high risk for diabetes, early intervention for sustained hyperglycemia and confirmed diabetes, and support of the patient requiring significant lifestyle changes will promote the best possible outcome.