Abstract
Many of you who are reading this article are advanced practitioners (APs) and experts in the management of complex patient symptoms. Despite managing “side effects” of treatment for years as a nurse, then an advanced practitioner, I did not fully comprehend the concepts of symptom management, symptom clusters, and complexity science until I took a course with a symptom management focus during my doctorate studies (Lee et al., 2016; Brant et al., 2009; Heylighen et al., 2006). In the course, we studied theoretical models hypothesizing that symptoms do not occur in isolation; rather, they occur in clusters that can interact with one another.
