Abstract
Hematopoietic stem cell transplant (HSCT) patients are at risk for and vulnerable to malnutrition throughout all phases of the transplant process. Patients can develop symptoms that make it difficult to maintain a balanced fluid, electrolyte, and nutrition status. Symptoms such as poor appetite, severe mucositis, and the complication of acute graft-vs.-host disease may develop as a result of this intensive therapy. These symptoms frequently lead to malnutrition, which has an impact on the physical, psychological, social, and spiritual well-being of patients and caregivers. This article highlights the importance of pretransplant screening and ongoing nutritional assessment, as well as the management of common complications and symptoms affecting nutritional status. Emphasis is placed on nutritional issues related specifically to patients during the acute phase of HSCT. Advanced practitioners caring for patients undergoing HSCT should work closely with a registered dietitian to develop a nutritional management plan that will prevent malnutrition and enhance the quality of life of patients and their families.