Donna Kinzler, DNP, ACNP-BC, AOCNP, on Mechanisms of Resistance to Anti-HER2 Therapy for Metastatic Breast Cancer

Donna Kinzler, DNP, ACNP-BC, AOCNP, of the Allegheny Health Network Cancer Institute, discusses a genomic analysis of 733 HER2-positive breast cancers, which identified recurrent pathway alterations associated with anti-HER2 resistance and new therapeutic vulnerabilities. The findings may help clinicians identify selective strategies to prevent disease progression (Abstract GS3-03).