JADPRO / Research and Scholarship

Research and Scholarship

Sharing Genomic Tumor Sequencing Results With Patients: Experiences of Advanced Practice Oncology Providers
Research and Scholarship

Sharing Genomic Tumor Sequencing Results With Patients: Experiences of Advanced Practice Oncology Providers

Lisa Stewart, PhD, ACNP, AOCNP, Anne Floyd Koci, PhD, RN, APRN-BC, FNP-BC, WHNP, FAAN, Tracy Brock Lowe, PhD, MS, RN, et al.

Advanced practice providers (APPs), defined as nurse practitioners, physician assistants, and pharmacists, frequently review and discuss molecular profiling (MP) results with patients. The aim of this study is to understand APP experienc...

November 4, 2024

Effects of a Revision to the Standard Admission Order Set on Laxative Prescribing for Opioid-Induced Constipation
Research and Scholarship

Effects of a Revision to the Standard Admission Order Set on Laxative Prescribing for Opioid-Induced Constipation

Shila Pandey, DNP, AGPCNP-BC, ACHPN, Jessica I. Goldberg, PhD, AGPCNP-BC, ACHPN, Kelly Haviland, PhD, RN, MSN, FNP, TGNB-C et al.

Oncology clinical practice guidelines recommend the use of osmotic and stimulant laxatives for the prevention and management of opioid-induced constipation, not stool softeners such as docusate sodium. Prescribing practices continue to f...

November 4, 2024

Evaluating the Impact of a Clinical Pharmacist in Patients Receiving New Chemotherapy for Breast Cancer: Analysis of a Pilot Study
Research and Scholarship

Evaluating the Impact of a Clinical Pharmacist in Patients Receiving New Chemotherapy for Breast Cancer: Analysis of a Pilot Study

Carissa Joelle Ganihong, PharmD, Anshika Singh, PharmD, BCOP, Roseanne DiMarco, PharmD, BCPS, BCOP et al.

At the Sidney Kimmel Cancer Center at Jefferson Health, a pilot program was developed to add an oncology clinical pharmacist to the breast cancer clinic. This study identified the pharmacist’s role in supportive care management and repor...

November 4, 2024

Impact of an Oncology Clinical Pharmacist Intervention on Clinical Trial Enrollment in The US Oncology Network's MYLUNG Consortium
Research and Scholarship

Impact of an Oncology Clinical Pharmacist Intervention on Clinical Trial Enrollment in The US Oncology Network's MYLUNG Consortium

Elizabeth Koselke, PharmD, BCOP, Lisa C. Kaspin-Powell, PhD, Shannon Hough, PharmD, BCOP, et al.

The US Oncology Network recently implemented a clinical pharmacist (ClinReview) initiative to provide remote clinical services to screen patients for enrollment onto MYLUNG Protocol 2. This study aims to evaluate the effect of the remote...

July 21, 2024

Improving Practice in a Head and Neck Oncology Clinic Using the PRO-CTCAE Tool
Research and Scholarship

Improving Practice in a Head and Neck Oncology Clinic Using the PRO-CTCAE Tool

Rose Ann Ruddy, DNP, MSN, RN, ACNP-BC, Brigit Carter, PhD, RN, CCRN, FAAN, Maryanne Giuliante, DNP, MBA, RN, GNP, ANP-C, NEA-BC, HEC-C, et al.

Background: Patients with head and neck cancer undergoing treatment report many side effects. Using patient-reported outcomes can assist with care management. Objectives: The purpose of this quality improvement project was to implement t...

July 19, 2024

Research and Scholarship

Infusion-Related Reaction Management With Amivantamab for EGFR Exon 20 Insertion Mutation NSCLC: A Practical Guide for Advanced Practitioners

Lindsay Dougherty, CRNP, DNP, Whitney E. Lewis, PharmD, BCOP, Meghan O’Neill, CRNP, MSN, et al.

Many targeted therapies to treat genetic mutations in non–small cell lung cancer (NSCLC) have been developed. Amivantamab(Rybrevant), a bispecific antibody targeting the epidermal growth factor receptor (EGFR) and mesenchymal-epithelial ...

May 22, 2024

Burnout and Resiliency Among Advanced Practice Providers in Oncology Care
Research and Scholarship

Burnout and Resiliency Among Advanced Practice Providers in Oncology Care

Abigail Baugh,(1) MPAS, PA-C, Victoria Reiser,(1) AG-ACDNP, BMTCN, OCN®, Jian Zhao,(2) PhD, RN, MS, Sara Jo Klein,(2) MS, BSN, RN, and Margaret Quinn Rosenzweig,(2) PhD, FNP-BC, AOCNP®, FAAN

Background: Occupational exhaustion, or burnout, is characterized with three components: emotional exhaustion, depersonalization, and sense of decreased personal accomplishment. Advanced practice providers (APPs) in oncology care are at ...

March 25, 2024

Research and Scholarship

Maintaining Survival While Improving Quality of Life: An Advanced Practitioner–Led Pilot Feasibility Study to Reduce Radiation Dose in Children With Brain Tumors

Jennifer L. Raybin,(1) PhD, RN, CPNP, Andrew Donson,(1) Nicholas K. Foreman,(1) MRCP, Rajeev Vibhakar,(1) MD, Michael H. Handler,(1) MD, and Arthur K. Liu,(2) MD, PhD

Purpose: Oncology advanced practitioners (APs) are on the front line in treating adverse effects. Among children with brain tumors, treatments such as craniospinal irradiation (CSI) cause neurocognitive injury, endocrinopathies, and otot...

January 24, 2024

Research and Scholarship

A Financial Toxicity Screening and Care Coordination Quality Improvement Program in a Gynecology Oncology Urban Practice

Tina Harris,(1) DNP, NP-C, AOCNP®, Julie Brinzo,(1) DNP, APRN, MBA, FNP-C, and Christopher Pell,(2) PhD

Background: Educating a multidisciplinary team on financial toxicity (FT) risk, screening, and care coordination is an approach to addressing gaps in care among newly diagnosed patients with stage III or IV cancer. Objective: The goal of...

January 22, 2024

Fostering Oral Chemotherapy Understanding and Safety (FOCUS) Project: Interventions for Improving Knowledge and Compliance With National Safety Standards
Research and Scholarship

Fostering Oral Chemotherapy Understanding and Safety (FOCUS) Project: Interventions for Improving Knowledge and Compliance With National Safety Standards

Jessica MacIntyre, DNP, MBA, APRN, NP-C, AOCNP, Rita D’Aoust, PhD, MS, RN,, Deborah Baker, DNP, CRNP, NEA-BC, , et al.

This quality improvement project evaluated provider and staff general knowledge on oral chemotherapy and national safety standards and the implementation and ease of use of an electronic medical record (EMR)-integrated chemotherapy docum...

January 5, 2024

Research and Scholarship

Capecitabine for Salvage Treatment of Patients With Heavily Pretreated Human Papillomavirus–Associated Oropharynx Cancer With Distant Metastases

Anna C. Cooper, PA-C, Casey A. Fazer, PA-C, Ashish V. Chintakuntlawar, MBBS, PhD, Harry E. Fuentes Bayne, MD, MS, Patrick W. McGarrah, MD, and Katharine A. R. Price, MD

Background: Patients with metastatic human papillomavirus–associated oropharyngeal cancer (HPV-OPC) have a median overall survival exceeding 2 years and are often candidates for multiple lines of palliative therapy. With the approval of ...

November 29, 2023

Research and Scholarship

Clinical Utility of the 31-Gene Expression Profile Test on the Management of Cutaneous Melanoma by Nurse Practitioners and Physician Assistants

Renata Block, MMS, PA-C, Deborah Patterson, MMS, PA-C, Jennifer J. Siegel, PhD, et al.

Objective: The 31-gene expression profile (31-GEP) can predict the risk of recurrence and metastasis in cutaneous melanoma (CM). We assessed the viewpoints and use of 31-GEP testing by physician assistants (PAs) and nurse practitioners (...

November 29, 2023

Research and Scholarship

Characterization and Management of Adverse Reactions in Patients With Unresectable Hepatocellular Carcinoma Treated With Lenvatinib

Anna Jones,(1) FNP-C, Paola Degregorio,(2) PA-C, Max W. Sung,(3) MD, 
Zahra Ramji,(4) BSN, Min Ren,(5) PhD, and Ari D. Baron,(1) MD

Aims: Advanced practice providers (APPs) play a vital role in monitoring for and managing adverse reactions (ARs). As lenvatinib ARs can resemble cirrhosis (commonly presenting with hepatocellular carcinoma [HCC]), APP input is important...

November 29, 2023

Research and Scholarship

Advanced Practitioners in Hematology and Oncology: State of the Workforce

Sandra Kurtin,(1) PhD, ANP-BC, AOCN®, FAPO, Carolyn Grande,(2) CRNP, AOCNP®, Megan May,(3) PharmD, BCOP, FAPO, FHOPA, Andrea Edwards,(4) PA-C, Steven Wei,(5) EdD, MS, MPH, PA-C, DFAPPA, Brianna Hoffner,(6) MSN, ANP-BC, AOCNP®, FAPO, and Wendy Vogel,(7) MSN, FNP, AOCNP®, FAPO

Advanced practitioners (APs), including nurse practitioners (NP), physician assistants (PA), pharmacists, and nurses with advanced degrees, including advanced practice registered nurses (APRNs), play a critical role in quality, timely, a...

November 6, 2023

Research and Scholarship

The Value of the Advanced Practitioner in Hematology and Oncology: Establishing Benchmarks

Sandra Kurtin,(1) PhD, ANP-BC, AOCN®, FAPO, Mailey L. Wilks,(2) DNP, APRN-CNP, Heather Koniarczyk,(2) MSN, APRN-CNP, AOCNP®, Nicole Deline,(3) MSN, APRN, FNP-C, AOCNP®, Sara Toth,(4) FNP-C, AOCNP®, AGN-BC, Andrea Edwards,(5) PA-C, Scott Rowley,(6) DNP, APRN-CNP, AOCNP®, Jason Astrin,(7) DMSc, MBA, PA-C, DFAAPA, and Wendy Vogel,(8) MSN, FNP, AOCNP®, FAPO

Advanced practitioners (APs) in hematology and oncology (heme/onc) practice and provide oversight across myriad settings, including outpatient, inpatient, specialty centers, infusion centers, and other care settings. Understanding the co...

November 6, 2023

Research and Scholarship

Patient-Reported Outcomes With Belantamab Mafodotin Treatment in Patients With Triple-Class Refractory Multiple Myeloma

Rakesh Popat,(1) BSc, MBBS, MRCP, FRCPath, PhD, Sagar Lonial,(2) MD, FACP, Peter M. Voorhees,(3) MD, Simona Degli Esposti,(4) MD, Boris Gorsh,(5a) PharmD, Ira Gupta,(5a) MD, Joanna Opalinska,(5) PhD, Sandhya Sapra,(5) PhD, Trisha Piontek,(5) BS, RN, Zangdong He,(5) PhD, David Kleinman,(6) MD, MBA, Debra Schaumberg,(7) SCD, OD, MPH, Antoine Regnault,(8) PhD, Juliette Meunier,(8) MSc, and Laurie Eliason,(5a) MPH

In the randomized phase II DREAMM-2 study, single-agent belantamab mafodotin demonstrated deep and durable responses and a manageable safety profile in triple-class refractory relapsed/refractory multiple myeloma (RRMM). We present patie...

September 19, 2023

Research and Scholarship

Anti-Spike Antibody Responses in Allogeneic Stem Cell Transplant Recipients to Two Doses of COVID-19 mRNA Vaccination: A Retrospective, Single-Center Analysis

Jaime L. Shahan, MPAS, PA-C, Robert H. Collins, MD, Prapti Patel, MD, Yazan F. Madanat, MD, and Madhuri Vusirikala, MD

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) recipients were excluded from the initial SARS-CoV-2 mRNA vaccination efficacy trials. Suboptimal vaccine responses have been reported in immunocompromised cohorts such as pa...

July 17, 2023

Research and Scholarship

Distress in Neuro-Oncology Patients and Its Implications for Communication

Carolin Roos,(1) Johannes Weller,(1) MD, Christiane Landwehr,(1) Anja Sciermoch,(2) Cathrina Duffy,(1) MD, Karoline Kohlmann,(1) MD, Christina Schaub,(1) MD, Theophilos Tzaridis,(1) MD, Matthias Schneider,(2) MD, Patrick Schuss,(2) MD, Ulrich Herrlinger,(1) MD, and Niklas Schäfer,(1) MD

Psychoemotional distress affects patients with cancer, including patients with a diagnosis of a malignant brain tumor. Empathy, professional expertise, and conversational skills are required to ensure successful communication with patien...

May 23, 2023

Research and Scholarship

Characteristics of Distress and Support Group Participation in Caregivers of Older Allogeneic Hematopoietic Cell Transplantation Patients: A Single Institution Retrospective Review

Theresa A. Elko,(1) MPAS, PA-C, Samantha Brown,(2) MS, Stephanie Lobaugh,(2) MS, Sean Devlin,(2) PhD, Ann A. Jakubowski,(1,5) MD, PhD, Miguel-Angel Perales,(1,5) MD, Molly A. Maloy,(1) MS, Allison J. Applebaum,(3) PhD, Sergio A. Giralt,(1,5) MD, Lauren Levy,(1) MS, PA-C, Anne Schneider,(4) LMSW, and Richard J. Lin,(1,5) MD, PhD

Older patients with hematologic malignancies are increasingly considered for allogeneic hematopoietic cell transplant (allo-HCT). However, older patients often have increased comorbidities and thus may require an increased level of post-...

March 22, 2023

Research and Scholarship

Predictors of Nurse Practitioner Prescription of Opioids for Cancer Pain: Quantitative Results

Erin McMenamin,(1,2) PhD, CRNP, Marye Kellermann,(3) PhD, CRNP, FAANP, Regina Cunningham,(1,2) PhD, FAAN, and Janet Selway,(3) DNSc, AGNP-C, CPNP-PC, FAANP

Background: Nurse practitioners (NPs) have assumed a greater role in the management of pain related to cancer. Several studies have associated adequate management of cancer pain with improved survival. Opioids are an essential treatment ...

January 18, 2023

Research and Scholarship

Serious Illness Conversation Training for Inpatient Medical Oncology Advanced Practice Providers: A Quality Improvement Project

Jo Clarke, DNP, ANP-BC, NP-C, ACNP-BC, APRN-CNP, AOCNP®, Mary Alice Momeyer, DNP, APRN-CNP, Robin Rosselet, DNP, RN, APRN-CNP, AOCN®, Loraine Sinnott, PhD, and Janine Overcash, PhD, APRN-CNP, FAANP, FAAN

Background: Hospitalized advanced cancer patients and their families are inadequately informed about their cancer diagnosis and prognosis, which limits educated and reasonable decision-making for their care and end-of-life planning. Obje...

January 18, 2023

Research and Scholarship

Interventions to Improve Advanced Practitioner Work-Related Quality of Life and Patient Satisfaction

Heather Jackson, PhD, FNP-BC, NEA-BC, FAANP, Olivia West, MSN, AG-ACNP-BC, Annie Austin, MSN, AGACNP-BC, AOCNP®, and Karline Peal, MBA, RTT

Background: Across the United States, an incremental need for cancer care continues to emerge. Specialty nurse practitioners and physician assistant teams have helped in meeting this demand. However, there is a need for evidence-based re...

January 18, 2023

Research and Scholarship

Adherence to Prophylactic Anticonvulsant Guidelines for Newly Diagnosed Brain Tumor Patients: A Quality Improvement Study

Dan Beverly Fu,(1) DNP, MBA, NP-C, Xiao-Tang Kong,(1) MD, PhD, Tener Goodwin Veenema,(2) PhD, MPH, MS, Daniela A. Bota,(1) MD, PhD, and Binu Koirala,(3) PhD, MGS, RN

Background and Purpose: Clinical guidelines suggest that prophylactic antiepileptic drugs (AEDs) should be given to newly diagnosed seizure-naive brain tumor patients for up to 1 week after craniotomy. Yet, data suggest that prophylactic...

November 21, 2022

Research and Scholarship

Management of Adverse Events in Early Clinical Trials by Advanced Practice Providers in the Outpatient Setting: The University of Texas MD Anderson Cancer Center Experience

Fedricker D. Barber (1), Erick Campbell (1), Yuko Yamamura (1), Clover J. Patterson (1), Audrey C. Hartnett (1), Holly Kinahan (1), Victoria A. Miller (1), Amanda L. Brink (1), Anna Poullard (1), Gabriele E. Urschel (1), Andre Brantley (1), Isabel G. Cepeda (1), Poonam Goswami (1), Sheena Charles (1), Shincy Philip (1), Sara Bresser (1), Sandra Musekiwa-Adjei (1), Nageli Perez (1), Hung Le (1), Penny Phillips (2), Vivek Subbiah (1), Funda Meric-Bernstam (1,3,4), and Ecaterina E. Dumbrava (1)

Background: Advanced practice providers (APPs) play important roles in enrolling, educating, and caring for patients in clinical trials. However, much remains unknown about the role of APPs in managing adverse events (AEs) in early (phas...

September 19, 2022

Research and Scholarship

Improving Cancer Care Delivery: Learnings for Oncology Nurses and Patient Navigation From a National Quality Survey

Jennifer Aversano,(1,2) MSN, RN, OCN®, BMTCN®, Leigh M. Boehmer,(3) PharmD, BCOP, and Alexander Spira,(4,5) MD, PhD, FACP

Background: Although implementation of patient navigation programs in clinical practice is widespread, heterogeneity exists in the design and delivery of these services. Greater clarity is required on competencies of personnel, delineati...

July 18, 2022

Research and Scholarship

Solid Pseudopapillary Neoplasm: A Single Institutional Case Series of a Rare Pancreatic Tumor

Kristen Oase,(1) MS, PA-C, Cheryl Meguid,(1) DNP, ACNP, Atsushi Oba,(1,2) Mohammed H. Al-Musawi,(1) MD, MSc, FIBMS-CTV, FRCS (Glasg), Alison Sheridan,(1) MD, Evan Norris,(1) MD, Sanjana Mehrotra,(1) MD, Mark A. Lovell,(3) MD, Richard D. Schulick,(1) MD, MBA, FACS, Steven A. Ahrendt,(1) MD, and Marco Del Chiaro,(1) MD, PhD, FACS

Purpose: Solid pseudopapillary neoplasms (SPN) are rare pancreatic cystic neoplasms with low malignant potential that tend to occur in young women. Due to the rarity of this disease, there are few large case series in the literature, and...

July 18, 2022

Research and Scholarship

Evaluation of Emergency Department Visits by Oncology Patients: A Running Comparison to Admissions and ED Visits Under the CMS OP-35 Ruling

Nada Alsuhebany,(1,2,3) BSPharm, PharmD, BCOP, Jamie Brown,(4) PharmD, MBA, Jacquelyne Echave,(5) and Ali McBride,(5) PharmD, MS, BCPS

Background: Cancer is the second leading cause of death in the United States. The incidence of emergency department (ED) visits by oncology patients has grown over the past years. Some ED visits are medically unnecessary and could be pre...

May 16, 2022

Research and Scholarship

Implementing a Clinical Decision Tool to Improve Oncologic Venous Thromboembolism Management

Jibran Majeed,(1,2) DNP, ACNP-BC, CCRN, Barbara S. Turner,(1) PhD, RN, FAAN, Deirdre Kelly,(2) ACNP-BC, Chester Poon,(2) Julie A. Thompson,(1) PhD, John Barrett,(3) DNP, FNP-BC, AGACNP-BC, and Gerald A. Soff,(4) MD

Background: Cancer patients with venous thromboembolic (VTE) disease are complex, and many factors must be considered when initiating anticoagulation management. Clinical decision support systems can aid in decision-making by utilizing g...

May 16, 2022

Research and Scholarship

Role of Oncology Advanced Practitioners to Enhance Clinical Research

Christa Braun-Inglis, DNP, APRN, FNP-BC, AOCNP®, Leigh M. Boehmer, PharmD, BCOP, Laura J. Zitella, MS, RN, ACNP-BC, AOCN®, Brianna Hoffner, MSN, ANP-BC, AOCNP®, Yurii B. Shvetsov, PhD, Jeffrey L. Berenberg, MD, Randall A. Oyer, MD, and Al B. Benson III, MD

Background: Oncology advanced practitioners (APs), including nurse practitioners, clinical nurse specialists, physician assistants, and clinical pharmacists contribute significantly to quality cancer care. Advanced practitioners enhance ...

March 19, 2022

Research and Scholarship

Impact of Music on Postoperative Pain, Anxiety, and Narcotic Use After Robotic Prostatectomy: A Randomized Controlled Trial

Kirtishri Mishra, MD, Erin Jesse, MD, Laura Bukavina, MD, MPH, Emily Sopko, APRN, CNP, Itunu Arojo, MD, Austin Fernstrum, MD, Al Ray III, MD, Amr Mahran, MD, MS, Adam Calaway, MD, Seneca Block, MA, MT-BC, and Lee Ponsky, MD

Background: Music is a safe and cost-effective intervention that can reduce postoperative pain and anxiety. We investigated the effects of music therapy on postoperative recovery in patients undergoing robotic-assisted laparoscopic prost...

March 19, 2022

Research and Scholarship

Shared Decision-Making in Managing Breakthrough Cancer Pain in Patients With Advanced Cancer

Jeannine M. Brant,(1) PhD, APRN, AOCN®, FAAN, Debra Wujcik,(2) PhD, RN, FAAN, William N. Dudley,(3) PhD, Alison Petok,(4) MSW, LSW, Brooke Worster,(4) MD, Diane Jones,(1) MSN, NP, Kim Bosket,(1) RN, BSN, OCN®, Christian Brady,(1) MSN, AGNP, APRN, and Carrie Tompkins Stricker,(4) PhD, RN, ANP-BC

Background: Pain is a significant problem in patients with cancer. Breakthrough cancer pain contributes to the pain experience, but it is often underassessed and underrecognized. Shared decision-making (SDM), where patient preferences, g...

January 19, 2022

Research and Scholarship

General and Unique Communication Skills Challenges for Advanced Practice Providers: A Mixed-Methods Study

Deborah Stein,(1) ACNP-BC, Kerry Cannity,(2) PhD, Richard Weiner,(1) NP, Shira Hichenberg,(1) Angelina Leon-Nastasi,(1) Smita Banerjee,(1) PhD, and Patricia Parker,(1) PhD

Aims: Advanced practice providers are a rapidly growing sector of the health-care field. Despite their relatively new place in the medical establishment, these providers are held to high standards of education, practice, and communicatio...

January 19, 2022

Research and Scholarship

Development and Implementation of an Advanced Practitioner–Led Survivorship Clinic for Patients Status Post Allogeneic Transplant

Linda K. Baer,(1) MSN, APRN, AOCNP®, Lauren Brister,(1) MSN, APRN, AOCNP®, and Susan R. Mazanec,(1,2) PhD, RN, AOCN®, FAAN

Background: Survivor recovery from hematopoietic cell transplantation (HCT) is long term, with significant physical and psychological morbidities that impact quality of life and reentry into personal and social lives. The optimal timing ...

November 24, 2021

Research and Scholarship

Assessment of Oncology Provider Knowledge and Cardiovascular Screening Practices: A Call for Heightened Screening

Katherine Albert,(1) DNP, FNP-BC, AOCNP®, Deborah Pollard,(1) PhD, RNC-OB, CNE, IBCLC, Jennifer Klemp,(2) PhD, MPH, MA, Lavanya Kondapalli,(3) MD, and Deborah Tuffield,(1) DNP, FNP-C, CCRN

Cardiac risk factors are known to compound the development of cardiotoxicities (CTx) in patients exposed to anthracycline (ANT) chemotherapy agents. National oncology and cardiology organizations have published recommendations for cardio...

November 24, 2021

Research and Scholarship

Short- and Long-Term Outcomes of Hematologic Malignancy Patients After Cardiopulmonary Resuscitation: Experience of a Large Oncology Center

Mary Lou Warren, DNP, APRN, CNS-CC, FCCM, Virginia V. Schneider, MPAS, PA-C, Yun Qing, MHS, PhD, Lei Feng, MS, Jeanne Y. Campbell, MPAS, PA-C, Jason W. Myers, ACNP-BC, Marian Von-Maszewski, MD, and Cristina Gutierrez, MD

Purpose: The objective of this study is to describe characteristics and short- and long-term outcomes of patients with hematologic malignancies who received cardiopulmonary resuscitation (CPR). Methods: A retrospective review was conduct...

September 21, 2021

Research and Scholarship

Understanding Attitudes and Roles of Oncology Advanced Practitioners in the Setting of Cancer Clinical Trials: A Pilot Study

Christa Braun-Inglis,(1,2) MS, APRN-Rx, FNP-BC, AOCNP®, Yurii B. Shvetsov,(2) PhD, Ashley Springer,(3) MSN, APRN-Rx, AGPCNP-BC, Valerie Ferguson,(4) MSN, APRN-Rx, FNP-C, AOCNP®, Tyler Workman,(5) MS, APRN-Rx, AGPCNS-BC, Dee Ann Omatsu,(6) MS, APRN-Rx, PNP-BC, CPON, Francisco Conde,(7) PhD, APRN-Rx, AOCNP®, FAAN, Erin O’Carroll Bantum,(2) PhD, and Jessica Rhee,(2) MD

Purpose: Oncology advanced practitioners (APs), including nurse practitioners, physician assistants, clinical nurse specialists, and pharmacists, are skilled health-care providers who contribute significantly to quality cancer care. Howe...

July 12, 2021

Research and Scholarship

A Pharmacist-Led Oral Chemotherapy Program’s Impact on Chronic Myeloid Leukemia Patient Satisfaction, Adherence, and Outcomes

Taylor Dennison,(1,2) PharmD, Allison M. Deal,(3) MS, Matthew Foster,(1,3) MD, John Valgus,(1,2) PharmD, MHA, BCOP, and Benyam Muluneh,(2) PharmD, BCOP, CPP

Patients with chronic myeloid leukemia (CML) can be treated with oral tyrosine kinase inhibitors (TKIs). Pharmacist-led oral chemotherapy programs (POCPs) can improve TKI adherence rates, but evaluation of patient satisfaction with such ...

March 17, 2021

Research and Scholarship

An Evaluation of the Use of Corticosteroids for the Management of Immune-Mediated Adverse Events in Cancer Patients Treated With Immune Checkpoint Inhibitors

Adrian Tsui,(1) PharmD, Lindsay Edmondson,(2) PharmD, BCOP, Justin Julius,(3) PharmD

Immune checkpoint inhibitors (ICIs) have gained prominence for the treatment of a variety of malignancies. However, they are associated with the development of immune-mediated adverse events (IMAEs). Appropriate management of IMAEs and s...

March 15, 2021

Research and Scholarship

Development, Implementation, and Patient Perspectives of the Women’s Integrative Sexual Health Program: A Program Designed to Address the Sexual Side Effects of Cancer Treatment

Lori A. Seaborne, MPAS, PA-C, Megan Peterson, DNP, David M. Kushner, MD, Janelle Sobecki, MD, MA, and Joanne K. Rash, MPAS, PA-C

Background: Advanced practitioners (APs) are a growing demographic in survivorship care. One goal of survivorship care is to manage consequences of cancer treatments. Sexual dysfunction from prior therapies can impact quality of life. Ad...

January 19, 2021

Research and Scholarship

Impact of Adherence to Ibrutinib on Clinical Outcomes in Real-World Patients With Chronic Lymphocytic Leukemia

Lauren M. Garner, PharmD, BCPPS, Theresa Kline, PharmD, BCPS, BCCP, Jordan Miller, PharmD, BCOP, CPP, Allison Deal, MS, Anqi Zhu, MS, PhD(c), Margaret R. Sketch, PharmD, MPH, Catherine C. Coombs, MD, and Benyam Muluneh, PharmD, BCOP, CPP

Background: Chronic lymphocytic leukemia (CLL) is a B-cell neoplasm with clonal expansion of small lymphocytes. Ibrutinib, an irreversible inhibitor of Bruton tyrosine kinase (BTK), is a first-line treatment option, and recent data sugge...

January 18, 2021

Research and Scholarship

Evaluation of the Role and Impact of Ambulatory Clinical Pharmacists in an Academic Comprehensive Cancer Center

Laura A. Meleis, PharmD, MS, BCPS, Mallika P. Patel, PharmD, CPP, Michael DeCoske, PharmD, BCPS, Meredith Moorman, PharmD, CPP, Paul W. Bush, PharmD, MBA, BCPS, FASHP, and Sally Barbour, PharmD, BCOP, CPP, FHOPA

Introduction: In recent years, there has been significant growth of ambulatory oncology pharmacy, yet there is a paucity of published studies on the clinical activities and impact of ambulatory oncology clinical pharmacists. At Duke Canc...

November 17, 2020

Research and Scholarship

Using a Quality Improvement Model to Implement Distress Screening in a Community Cancer Setting

Nancy Jo Bush,(1) DNP, RN, MA, AOCN®, FAAN, Joy R. Goebel,(2) RN, PhD, FPCN, Kholoud Hardan-Khalil,(2) PhD, RN, and Kayo Matsumoto,(3) MS, MFT

Background: Quality cancer care includes routine screening for psychosocial distress. This quality improvement project focused on the implementation of distress screening at a licensed affiliate of Cancer Support Community, a community-b...

November 17, 2020

Research and Scholarship

Revisiting Infectious Complications Following Total Parenteral Nutrition Use During Hematopoietic Stem Cell Transplantation

Halina Rubin,(1) RPh, Jayesh Mehta,(1,2) MD, Jessica L. Fong,(1) PharmD, Deborah Greenberg,(1) PharmD, Solomiya Gruschak,(1,2) BS, and Steven Trifilio,(1,2) RPh

Background: Total parenteral nutrition (TPN) is frequently used to manage caloric needs during hematopoietic stem cell transplantation (HSCT). Previous studies in transplant patients who received TPN have reported widely discordant resul...

September 23, 2020

Research and Scholarship

Utilizing a Palliative Care Screening Tool in Patients With Glioblastoma

Jung Young Kim,(1) DNP, APRN, ANP, Katherine B. Peters,(1) MD, PhD, FAAN, James E. Herndon II,(2) PhD, and Mary Lou Affronti,(1) DNP, RN, MHSc, ANP

Patients with glioblastoma have poor overall survival and experience significant burden from neurologic decline and adverse treatment effects. Despite the well-known benefits of early palliative care integration with oncology care, utili...

September 23, 2020

Research and Scholarship

Perceptions of Health-Care Workers of the Cost and Safety of Oral Oncolytic Agents for Patients: A Survey

Madeline Tompkinson,(1) PharmD, Kelly Fine,(2) RPh, FAzPA, Dean Gruber,(3) RPh, Ivo Abraham,(4) PhD, RN, and Ali McBride,(5) PharmD, MS, BCPA, BCOP

Purpose: The number of newly approved cancer medications continues to grow; many of these newly approved medications are oral agents. Oral oncolytic agents have advantages including patient convenience, prolonged drug exposure, and nonin...

May 27, 2020

Research and Scholarship

Understanding Barriers to Oral Therapy Adherence in Adults With Acute Myeloid Leukemia

Ashley Leak Bryant,(1) PhD, RN-BC, OCN®, Ya-Ning Chan,(1) MSN, RN, Jaime Richardson,(1) BSN, RN, OCN®, CCRP, Matthew Foster,(1) MD, Susie Owenby,(2) BSN, RN, and Debra Wujcik,(2) PhD, RN

Acute myeloid leukemia (AML) is a disease of older adults, with a median age at diagnosis of 68 years. The availability of oral anticancer medications has increased, although the standard treatment for AML remains in intravenous form. We...

May 26, 2020

Research and Scholarship

Burnout, Workplace Factors, and Intent to Leave Among Hematology/Oncology Nurse Practitioners

Laura Bourdeanu,(1) NP, PhD, Qiuping (Pearl) Zhou,(2) PhD, RN, Michelle DeSamper,(3) Kaitlin Anne Pericak,(4) MA, and Arlene Pericak,(2) FNP-BC, DA

Background: Burnout and intent to leave have been well documented in oncology/hematology health-care professionals, with a potentially detrimental effect on the patient-provider relationship and job satisfaction. With the recommended cha...

March 18, 2020

Research and Scholarship

An Advanced Practice Provider Initiative for Delirium Management in the ICU

Sarah Rebal, MS, RN, ACNP-BC, Caroline Shirzadi, MS, RN, ACNP-BC, Jennifer Agatep, Ms, RN, AGACNP, Konstantina Matsoukas, MLIS, Kay See Tan, PhD, Kenneth Seier, MS, Yesne Alici, MD, Beatriz Korc-Grodzicki, MD, PhD, and Louis Voigt, MD

Delirium is the most common neuropsychiatric challenge in cancer patients, particularly in the critically ill population. Without a screening method and constant vigilance by providers, delirium is often misdiagnosed. The purpose of our ...

March 18, 2020

Research and Scholarship

Implementation of Survivorship Care Plans in Patients With Glioblastoma

Casey B. Brown,(1) DNP, RN, AGPCNP-BC, Deborah Allen,(1) PhD, RN, CNS, FNP-BC, AOCNP®, Christina Cone,(1) DNP, APRN, ANP-BC, AOCNP®, and Susan M. Schneider,(2) PhD, RN, AOCN®, ACNS-BC, FAAN

Background: The outcomes and survival of patients diagnosed with glioblastoma are improving due to advancements in therapy and better symptom management. Focusing on survivorship is an important initiative for these patients. A quality i...

January 22, 2020

Current Issue
Sep/Oct 2024 Cover
Sep/Oct 2024 Cover Art
Vol 15 No 6 Sep/Oct 2024

Carcinoid Heart Disease

Nicole Kuhnly, MS, ACNPC-AG, Jessica Shank Coviello, DNP, APRN, ANP-BC, Catherine A. Kobza, MSN, AGACNP-BC, Et al.

September 16, 2024

Table of Contents Archive
Recent Issues
Volume 15, Number 6 (Sep/Oct 2024)
Volume 15, Number 5 (Jul/Aug 2024)
Volume 15, Number 4 (May/Jun 2024)
Volume 15, Number 3 (Apr 2024)